Researchers took a closer look at the current debate over the origin of enzymatic catalytic power and proposes a mechanism that unites the opposing theories. The enzymes found in living organisms have ...

The snapshots reveal key reactions steps. At 0 ms, water molecules occupy the substrate-binding site. At 50 ms, a substrate-cofactor intermediate forms. At 100 ms, the product is released, and the ...

Chemists created an enzyme with boronic acid at its reactive center. This approach can produce more selective reactions with boron, and allows the use of directed evolution to improve its catalytic ...

A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...

Living cells are bustling with molecular machines that constantly process energy, matter, and information. Among these machines, proteins stand out, with enzymes being the most notable. These ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...

Enzymes accelerate reactions by helping to lower the activation energy needed to start them. But how enzymes achieve this has been the subject of intense debate. A research team from Texas and China ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...