A new generation of engineered immune cell destroys cancer cells in mice 1 as effectively as conventional CAR-T-cell ...

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

A UCLA research team has identified the best design for a promising new type of immunotherapy that could be mass-produced to ...

Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...

Cardiologists have spent decades trying to stabilize the fatty plaques that clog arteries, but a new wave of immunotherapy is going after the diseased cells at the heart of the problem. In mice, an ...

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

Please provide your email address to receive an email when new articles are posted on . After first generating excitement in late 2022, this year was a bonanza for news about chimeric antigen receptor ...

Please provide your email address to receive an email when new articles are posted on . Multiple CAR T-cell therapy strategies have exhibited clinical activity in recurrent glioblastoma. Early data ...