Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

The human Y chromosome, responsible for determining male sex, finally has gotten an end-to-end examination. The Y chromosome is the smallest of the human chromosomes. “In the old time, people thought ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

In 2002, evolutionary biologist Jenny Graves shared a controversial calculation. The human Y chromosome, she wrote two years later in a commentary, "is running out of time." The male-determining sex ...

Analyzing genetic data from nearly 140,000 IVF embryos, researchers linked maternal DNA variants to increased risk of ...