A major advance in cell biology has revealed how our cells safeguard their genetic material during one of the most vulnerable moments in their life cycle. The study identifies a specific protein ...

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

Human disease including cancer arises from disfunction of essential processes within a cell. One essential cellular process is the copying of the genomic DNA—the road map of cells—followed by ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a ...

Researchers at The University of Hong Kong (HKU) have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer.

CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.