When the liver fails, brain function changes. Acute-on-chronic liver failure is manifested initially as abnormal behavior and compromised cognition. In the absence of preexisting disease, acute, ...

The associated underlying disease is used to classify hepatic encephalopathy: type A is related to acute liver injury, type B is related to portosystemic shunting, and type C is related to cirrhosis.

Arun B. Jesudian, MD: So now let’s shift gears and really talk about management of the patient with hepatic encephalopathy [HE] and treatment. And Steve, we have societies that publish guidelines—in ...

Ammonia levels are orchestrated by a series of complex interrelated pathways in which the urea cycle has a central role. Liver dysfunction leads to an accumulation of ammonia, which is toxic and is ...

Hepatic encephalopathy (HE) is a neuropsychiatric disorder linked to both acute and chronic liver failure and/or portosystemic shunting, caused by the accumulation of neurotoxic substances, such as ...

Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak. The resulting ...

"Encephalopathy" means damage or disease that affects the brain. It happens when there’s been a change in the way your brain works or a change in your body that affects your brain. Those changes lead ...

Arun B. Jesudian, MD: We’ve mentioned GI [gastrointestinal] bleeding, we’ve mentioned hypovolemia, dehydration. Elliot, before you alluded to infections [as] a problem in this population. How do those ...

To the Editor: In the review article on hepatic encephalopathy (Oct. 27 issue), 1 Wijdicks provides critical information on the pathophysiological features and the management of this condition. The ...