A modified pig liver transplanted into a human patient appears to have functioned normally for the duration of the investigation with no signs of rejection. For 10 days, the liver performed its basic ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks ...

Carnegie Mellon bioprinted liver tissue works 2-4 weeks, potentially saving lives as temporary bridge while patients await ...

In the short term, these multi-zonal liver organoids will help scientists shed new light on diseases including diabetes, drug-induced liver injury, alcohol-related liver disease, and viral hepatitis.

The university's scientists have received a $28.5 million award from the Advanced Research Projects Agency for Health to develop a transplantable 3D-printed liver patch. The initiative ...

A human model of immune-driven liver injury Some drugs that pass early safety testing can still cause idiosyncratic drug-induced liver injury (iDILI)—a rare immune reaction that can lead to severe ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

In a medical first, doctors have successfully transplanted a pig liver into a human patient, who subsequently lived for almost half a year. The 71-year-old man's own liver was irreversibly scarred by ...

Technically speaking, the transplant was a success.

Researchers developed TLC-2716, a liver- and gut-targeted drug that selectively reduced LXR activity, lowering triglycerides, ...