What if cattle were selected not only for their productivity, but also for their resistance to disease? A study conducted by ...

Samira Kiani, M.D, associate professor of pathology, member of the Pittsburgh Liver Research Center and the McGowan Institute for Regenerative Medicine. Credit: University of Pittsburgh Gene therapy ...

Study suggests that persistently activated ATF6α is a tumor driver, a potential stratification marker for immunotherapy response, and a therapeutic target for HCC.

Chronic activation of the stress protein ATF6α promotes aggressive liver tumors by rewiring glucose metabolism and ...

CNS-directed AAV gene therapy shows milder immune responses compared to systemic administration, reducing peripheral immune activation and systemic toxicities. Direct CNS delivery can bypass ...

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

In cellular and animal models of neuroblastoma, small cell lung cancer and colon cancer, this strategy reduces tumours, ...

An infection with Epstein-Barr virus is a nonevent for most people. But for a subset, the virus can contribute to chronic ...