We previously analysed the OFC3 candidate region using a sample of 40 multiplex pedigrees and microsatellite markers, and obtained evidence of linkage and linkage disequilibrium with APM and TDT ...

Linkage disequilibrium (LD) refers to the correlation among neighboring alleles, reflecting common haplotype ancestry. In the May 10 Nature, Reich et al. describe a systematic, genome-wide analysis of ...

Despite growing interest in the use of transmission/disequilibrium test (TDT)-type analysis in association studies, there has been surprisingly scant attention paid ...

This is a preview. Log in through your library . Abstract 1,004 unrelated Danes were typed for HLA-A,B antigens and glyoxalase I (GLO), and investigations for linkage disequilibrium between the HLA ...

After years of failed promises that researchers would find genes linked to cancers, heart disease, and other complex human ailments, two independent research teams, using different approaches, ...