Patients 1 and 2 had bone marrow cytogenetic analyses and reverse transcriptase-polymerase chain reaction (RT-PCR) screening for chromosomal translocations performed at initial presentation. Patient 3 ...

SAN DIEGO -- Nearly two-thirds of patients with relapsed or refractory KMT2A-rearranged acute leukemia responded to an investigational oral menin inhibitor, a phase II trial showed. Among 57 children ...

B-ALL is the most common paediatric cancer and, over the years and thanks to a very effective treatment based on glucocorticoids, its 5-year survival rates have reached 85% and beyond. However, there ...

We often think of blood as the uniform red liquid encountered after a kitchen accident or at the doctor’s office. While this is true, on a microscopic level blood is made up of highly heterogeneous ...

Researchers from The University of Texas MD Anderson Cancer Center showed that inhibiting menin with revumenib, previously known as SNDX-5613, yielded encouraging responses for advanced acute ...