The idea that depression is caused by a chemical imbalance in the brain is more than half a century old. The reality is more ...

Depression in older adults may sometimes signal the early stages of Parkinson’s disease or Lewy body dementia. Researchers found that depression often appears years before diagnosis and remains ...

When I was first diagnosed with depression, many people—even those who knew me well, who cared about me—responded with the opposite of what I needed to hear. This was partly because they didn’t ...

While these types of depression are similar, they may have different causes and require different treatments. Depression is one of the most common mental health conditions, affecting tens of millions ...

Globally, over 280 million people have depression. But if you were to ask a random sample of 1,000 people to describe their depression, you would have a low chance of finding two people who have the ...

We don’t experience depression uniformly, and a new study finds that some symptoms may be more strongly linked with ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Depression and anxiety are linked to progression and increased mortality in Huntington disease, but antidepressants may ...