Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

In most cases, the damage is linked to mutations in the OPA1 gene, which interfere with mitochondrial function (how cells make energy and stay healthy). New research led by Thomas Schwarz, Ph.D., and ...

In 2016, sarcopenia was recognized as a disease and given an ICD-10-CM code (M62.84). 3,4 However, the originating causes of sarcopenia are largely unknown and have no clinical treatments at present, ...

In a recent study published in Nature Metabolism, researchers found that feeding a high-fat diet (HFD) causes mitochondrial dysfunction and fragmentation in white adipocytes in mice. Study: Obesity ...