Antibodies against CD47, an antiphagocytic cell surface molecule produced by some cancer cells, could be an effective treatment for paediatric brain tumours, according to new research. Anti-CD47 ...

Phagocytes such as macrophages and neutrophils contain multiple lysosomes, which possess a variety of digestive enzymes. Upon stimulation, phagocytes secrete these digestive enzymes through a process ...

Mononuclear phagocytes can both promote and inhibit inflammation. A team has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different ...

Every day, billions of damaged or unnecessary cells die and are swept away by the immune system’s cleanup crew—phagocytes. But when that clearance falters, dangerous cells can linger, fueling cancer ...

When cells die or the body no longer needs them, phagocytic cells arrive to engulf them. This process relies upon the cells destined for destruction to express a protein that serves as an “eat me” ...

ONE designates as phagocytes cells endowed with the ability to ingest particulate matter such as bacteria, cellular debris and colloidal dyes. The ingested material may or may not be digested within ...

The engulfment ability of a phagocyte is controlled by its mitochondrial membrane potential (MMP), according to a study by Ravichandran and colleagues. The authors reasoned that the 'ingestion' of ...

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