Lymphomas are a heterogeneous group of malignancies of the lymphoid system that account for ∼75 000 new tumor cases every year. In lymphoma patients, activation of the fibrinolytic system is ...
In order to best target proteinases for inhibition in a relatively selective manner, the types and quantities of proteases available at the primary site and secondary sites such as bone must be ...
Team finds closed plasminogen conformation transiently exposes binding site. Scientists report the X-ray crystal structure of full-length human plasminogen, and describe binding of blood clots to ...