Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of ...

Those with an increased risk of bleeding may require platelet transfusion in various medical situations such as after a severe injury or prior to major surgery, to prevent bleeding or excessive blood ...

LOS ANGELES, Dec 10 (Reuters) - Amgen Inc said on Monday its experimental drug AMG 531 increased platelet production in adults with a bleeding disorder known as chronic immune thrombocytopenic purpura ...

They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This decisive process is regulated by the innate immune system ...