A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

A defect in mitochondrial tRNA modification impairs the proper formation of mitochondrial OXPHOS complexes, which results in iron transmigration from mitochondria to cytosol. Excess cytosolic iron ...