A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

Calcium transport into and out of mitochondria -- the powerhouses of cells -- is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

Scientists demonstrated that glial fibrillary acidic protein (GFAP) promotes mitochondrial fission rather than blocking fusion. The genetic disorder Alexander disease is caused by mutations in the ...

For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery of mitochondria—the organelles ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

A defect in mitochondrial tRNA modification impairs the proper formation of mitochondrial OXPHOS complexes, which results in iron transmigration from mitochondria to cytosol. Excess cytosolic iron ...