The production of red blood cells from stem cells has emerged as a transformative approach to address chronic blood shortages and meet the increasing demand for transfusion therapies. By harnessing ...

A research team has discovered a mechanism in which blood stem cells respond to acute, severe anemia, through lipoprotein metabolism modification. It has been known how immediate erythroid precursors ...

If CXCR4 is removed from the cells, red blood cell development stops at subsequent stages, and bone marrow production drops severely. That loss helps to confirm just how important the CXCL12-CXCR4 ...

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into mature red blood cells. Ordinarily, glutamine is broken down by stem cells ...

A new Northwestern Medicine study has revealed how a common inherited mutation disrupts red blood cell development and sparks inflammation that can lead to leukemia, according to findings published in ...

Myelosuppression, or bone marrow suppression, is defined as a decrease in the ability of the bone marrow to produce blood cells. This may result in a lack of red blood cells (anemia), white blood ...

A change in the volume of red blood cells has been documented in astronauts since the earliest space missions. Thanks to an experiment conducted aboard the International Space Station, a research team ...

In their quest for safe, mass-producible artificial blood, geneticists have long struggled. Our limited knowledge of genetic pathways that govern the development of blood has kept us from producing ...