An antibody that binds to the latent form of transforming growth factor-β1 (TGF-β1) prevented its release into the extracellular matrix and reduced the progression of fibrosis in the kidney. TGF-β is ...
Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...
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Kidney fibrosis: The dangerous condition that can shut down renal function; causes and treatment
When people hear "kidney issue," they typically envision something glaring and painful such as kidney stones or infections. These are commonly accompanied by distinct warning signs, allowing for rapid ...
ATYR0101 interacts with LTBP-1 to induce myofibroblast apoptosis through a novel anti-fibrotic mechanism to reduce fibrosis and fibrotic markers in models of lung and kidney fibrosis. SAN DIEGO, Dec.
In a recent study published in Nature Metabolism, researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis. Fibrogenesis is a defensive reaction to ...
Latest Assays Can Improve Prostate Cancer Workup Incorporating a combination of urinary biomarkers may help identify patients at the highest risk for CKD progression. Adding urinary biomarkers to the ...
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