A holistic inquiry into how toxic tau impacts synapses provides a new take on the processes that lead to neuronal dysfunction ...

Scientists have discovered that the adolescent brain does more than prune old connections. During the teen years, it actively builds dense new clusters of synapses in specific parts of neurons. These ...

Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same ...

The next time you reach for a memory or make a quick choice, a storm of tiny signals races through your brain. Scientists can ...

Plastic and thus modifiable neurons lose their function at old age, new research in fruit flies reveals.

For more than a century, the story of the brain has been told as a tale of neurons, with every thought and memory traced to their electrical chatter. That narrative is now being rewritten as evidence ...

One of the brain's most celebrated qualities is its adaptability. Changes to neural circuits, whose connections are continually adjusted as we experience and interact with the world, are key to how we ...

New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest ...

Experimental electron micrograph of purified synaptic vesicles (upper). Synaptic vesicles automatically identified in the image with a new computer program are highlighted with different colours and ...

Stressed brain cells can survive longer by slowing sugar use, revealing a short-term protective response that later turns ...