Researchers say the deep learning model may help to create leads for new cancer diagnostics, patient stratification, and future therapies.

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

DNA is commonly referred to as the instruction manual of the cell – a compendium of thousands of genes, the particular sequences of which determine the activities of the proteins they encode. But, in ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

Yeast is a single cell eukaryotic organism, that incites in this Irish scientist an intense memory of the smell of brewing Guinness, wafting down the River Liffey on a drizzly Dublin day as I sit at ...

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...

A research team introduces a new large-scale study on human transcription factors combining two state-of-the art interactomics methods that allow rapid identification of protein-protein interactions ...