Bioengineers have developed a generalizable method to address 'off-target' binding, a significant problem in the field of synthetic biology. Taking a cue from nature, the researchers showed they could ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like ...

HOUSTON – (Aug. 15, 2023) – Bioengineers can tailor the genomes of cells to create “cellular therapies” that fight disease, but they have found it difficult to design specialized activating proteins ...